ALWAYS keep your Frenzy at 10 stacks when you're fighting, just tap Frenzy once each time when you see the timing for the stacks disappearing and the timer will reset again. Bash till you are out of fury, Frenzy a little again and continue bashing away. Stack your Frenzy to 10 stacks and by this time, your fury should be full with your Ancients busy hitting away at the same time.Most importantly, this activates your IK's set damage bonus! Your Ancients are your sponge for damage and I can't stress how important it is to have them up all the time! Berserker mode grants you increased movement speed to move to crowds of mobs quicker, and also provides some dodge chance along the way. ALWAYS keep your Call of the Ancients and Wrath of the Berserker on no matter what happens. The minute you see the first crowd of mobs, activate Wrath of the Berserker. Activate Call of the Ancients and War Cry the minute you start a rift, this will give you enough fury to immediately activate Battle Rage.

Wrath of the Berserker with Insanity rune another core for IK's set but with the rune we are talking about a 50% increase in damage here!!!!.

Then again, it is extremely flexible depending on the difficulty you are aiming for.

War Cry with Impunity rune this is another good damage reduction in my opinion giving you 20% additional armour and all resist with the rune.

Alternatively, you can go for Ignore Pain for more combat survivability or Sprint or Furious Charge for better escape and crowd control. I am super greedy so I wanted this since it increases my damage by 15% with this rune, and additional 3% critical chance. Battle Rage with Maruder's Rage rune this slot is actually quite flexible depending on how damage greedy you are.Call of the Ancients with Together as One rune of course we need these buddies for IK's damage bonus and having that rune would already reduce our damage received by a whopping 50%!.Bash with Pulverize rune some might want to consider Punish rune for even greater damage but I personally prefer Pulverize not just because of how cool it looks having fire blasting out of your fist but also because it changes it to an area damage.Add this with the primary effect of Frenzy where you gain 15% attack speed for each stack (150% for 10).starting to see how scary you can be? Frenzy with Maniac rune is selected, this grants you 2.5% increase in your overall damage with each stack and since you have 10 stacks all the time, that makes it a free 25% increase in damage always.

Diablo 3 immortal kings set